Impact of comorbid anxiety disorders and obsessive-compulsive disorder on 24-month clinical outcomes of bipolar I disorder

SW Kim; L Berk; J Kulkarni; S Dodd; A De Castella; PB Fitzgerald; GP Amminger; M Berk

Journal article

Impact of comorbid anxiety disorders and obsessive-compulsive disorder on 24-month clinical outcomes of bipolar I disorder

SW Kim, L Berk, J Kulkarni, S Dodd, A De Castella, PB Fitzgerald, GP Amminger, M Berk

Journal of Affective Disorders | ELSEVIER SCIENCE BV | Published : 2014

DOI: 10.1016/j.jad.2014.05.017

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Abstract

Background This study investigated the impact of comorbid obsessive-compulsive disorder (OCD) and four anxiety disorders [panic disorder (PD), agoraphobia, social anxiety disorder (SAD), and generalized anxiety disorder (GAD)] on the clinical outcomes of bipolar disorder. Methods This study analysed data of 174 patients with bipolar I disorder who participated in the prospective observational study. Participants were assessed every 3 months for 24 months. The primary outcome measure was the achievement of symptomatic remission, defined by a total score on the Young Mania Rating Scale (YMRS) of ≤12 and a total score on the 21-item Hamilton Depression Rating Scale (HAMD-21) of ≤8. Results Como..

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University of Melbourne Researchers

Paul Amminger Author

Michael Berk Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

The Bipolar Comprehensive Outcomes Study (BCOS) was funded by an unconditional research grant provided by Eli Lilly Australia. Lilly had no role in the collection, analysis, interpretation of data, the writing of the report, and in the decision to submit the paper for publication.